Publications

PAPERS

2018


Alberio L, Locarno A, Saponaro A, Romano E, Bercier V, Albadri S, Simeoni F, Moleri S, Pelucchi S, Porro A, Marcello E, Barsotti N, Kukovetz K, Boender AJ, Contestabile A, Luo S, Moutal A, Ji Y, Romani G, Beltrame M, Del Bene F, Di Luca M, Khanna R, Colecraft HM, Pasqualetti M, Thiel G, Tonini R, Moroni A.
A light-gated potassium channel for sustained neuronal inhibition.
Nat Methods.. 2018 Nov;15(11):969-976. doi: 10.1038/s41592-018-0186-9.
https://www.nature.com/articles/s41592-018-0186-9

Greiner T, Moroni A, Van Etten JL, Thiel G.
Genes for Membrane Transport Proteins: Not So Rare in Viruses.
Viruses. 2018 Aug 26;10(9). pii: E456. doi: 10.3390/v10090456.
https://www.mdpi.com/1999-4915/10/9/456

Gross C, Saponaro A, Santoro B, Moroni A, Thiel G, Hamacher K.
Mechanical transduction of cytoplasmic-to-transmembrane-domain movements in a hyperpolarization-activated cyclic nucleotide-gated cation channel.
J Biol Chem. 2018 Aug 17;293(33):12908-12918. doi: 10.1074/jbc.RA118.002139.
http://www.jbc.org/cgi/pmidlookup?view=long&pmid=29936413

Saponaro A, Cantini F, Porro A, Bucchi A, DiFrancesco D, Maione V, Donadoni C, Introini B, Mesirca P, Mangoni ME, Thiel G, Banci L, Santoro B, Moroni A.
A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.
Elife. 2018 Jun 20;7. pii: e35753. doi: 10.7554/eLife.35753.
https://doi.org/10.7554/eLife.35753

Bjarnsholt T, Buhlin K, Dufrêne YF, Gomelsky M, Moroni A, Ramstedt M, Rumbaugh KP, Schulte T, Sun L, Åkerlund B, Römling U.
Biofilm formation – what we can learn from recent developments.
J Intern Med. 2018 Oct;284(4):332-345. doi: 10.1111/joim.12782.
https://doi.org/10.1111/joim.12782

Voos P, Fuck S, Weipert F, Babel L, Tandl D, Meckel T, Hehlgans S, Fournier C, Moroni A, Rödel F, Thiel G.
Ionizing Radiation Induces Morphological Changes and Immunological Modulation of Jurkat Cells.
Front Immunol. 2018 Apr 30;9:922. doi: 10.3389/fimmu.2018.00922. eCollection 2018.
https://dx.doi.org/10.3389/fimmu.2018.00922

Rondelli V, Del Favero E, Brocca P, Fragneto G, Trapp M, Mauri L, Ciampa MG, Romani G, Braun CJ, Winterstein L, Schroeder I, Thiel G, Moroni A, Cantu’ L.
Directional K+ channel insertion in a single phospholipid bilayer: Neutron reflectometry and electrophysiology in the joint exploration of a model membrane functional platform.
Biochim Biophys Acta Gen Subj. 2018 Aug;1862(8):1742-1750. doi: 10.1016/j.bbagen.2018.05.007.
https://linkinghub.elsevier.com/retrieve/pii/S0304-4165(18)30139-9

Winterstein LM, Kukovetz K, Rauh O, Turman DL, Braun C, Moroni A, Schroeder I, Thiel G.
Reconstitution and functional characterization of ion channels from nanodiscs in lipid bilayers.
J Gen Physiol. 2018 Apr 2;150(4):637-646. doi: 10.1085/jgp.201711904.
http://jgp.rupress.org/cgi/pmidlookup?view=long&pmid=29487088

Servatius H, Porro A, Pless SA, Schaller A, Asatryan B, Tanner H, de Marchi SF, Roten L, Seiler J, Haeberlin A, Baldinger SH, Noti F, Lam A, Fuhrer J, Moroni A, Medeiros-Domingo A.
Phenotypic Spectrum of HCN4 Mutations: A Clinical Case.
Circ Genom Precis Med. 2018 Feb;11(2):e002033. doi: 10.1161/CIRCGEN.117.002033.
https://www.ncbi.nlm.nih.gov/pubmed/29440115


2017

Rauh O, Hansen UP, Mach S, Hartel AJW, Shepard KL, Thiel G, Schroeder I. Extended beta distributions open the access to fast gating in bilayer experiments-assigning the voltage-dependent gating to the selectivity filter. FEBS Lett. 2017 Dec;591(23):3850-3860. doi: 10.1002/1873-3468.12898.
http://onlinelibrary.wiley.com/doi/10.1002/1873-3468.12898/abstract

Saponaro A, Porro A, Chaves-Sanjuan A, Nardini M, Rauh O, Thiel G, Moroni A. Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins. Plant Cell. 2017 Oct;29(10):2570-2580. doi: 10.1105/tpc.17.00375.
http://www.plantcell.org/content/29/10/2570.long

Rauh O, Urban M, Henkes LM, Winterstein T, Greiner T, Van Etten JL, Moroni A, Kast SM, Thiel G, Schroeder I. Identification of Intrahelical Bifurcated H-Bonds as a New Type of Gate in K+ Channels. J Am Chem Soc. 2017 Jun 7;139(22):7494-7503. doi: 10.1021/jacs.7b01158.
https://pubs.acs.org/doi/10.1021/jacs.7b01158

Cosentino C, Alberio L, Thiel G, Moroni A. Yeast-Based Screening System for the Selection of Functional Light-Driven K+ Channels. Methods Mol Biol. 2017;1596:271-285. doi: 10.1007/978-1-4939-6940-1_17.
https://link.springer.com/protocol/10.1007%2F978-1-4939-6940-1_17

Weißgraeber S, Saponaro A, Thiel G, Hamacher K. A reduced mechanical model for cAMP-modulated gating in HCN channels. Sci Rep. 2017 Jan 11;7:40168. doi: 10.1038/srep40168.
https://www.nature.com/articles/srep40168